The 2018 ACC/AHA Guidelines for Cholesterol Management in Adult Patients

Activity Preview

In November 2018, the 2018 American College of Cardiology/American Heart Association (ACC/AHA) Guideline on the Management of Blood Cholesterol was published. The goal of the new guideline was to answer the question, “In adults ≥ 20 years of age with clinical atherosclerotic disease (e.g., coronary heart disease [CHD], peripheral artery disease, or cardiovascular disease [CVD]) or at high risk of atherosclerotic cardiovascular disease (ASCVD), what are the magnitude of benefit (absolute reduction; number needed to treat [NNT]) in individual endpoints and composite ischemic events (e.g., fatal cardiovascular event, nonfatal myocardial infarction [MI], nonfatal stroke, unstable angina/revascularization) and magnitude of harm (absolute increase; number needed to harm [NNH]) in terms of adverse events (e.g., cancer, rhabdomyolysis, diabetes) derived from LDL-C lowering in large randomized controlled trials (RCTs) (>1,000 participants and originally designed to last >12 months) with statin therapy plus a second lipid-modifying agent compared with statin alone?”

Learning Objectives

At the completion of this activity, the pharmacist and pharmacist technician will be able to:

  1. Set appropriate LDL-C thresholds according to a patient􀂶s current atherosclerotic cardiovascular disease (ASCVD) status and 10-year risk
  2. Develop an optimal non-pharmacologic and pharmacologic treatment plan for a patient with dyslipidemia according to practice guidelines and clinical trial evidence
  3. Implement appropriate monitoring and follow-up of patients with dyslipidemia, including adherence to their treatment plan, repeat lipid measurements and dose adjustments as needed

Activity type: Knowledge-based

Target Audience: Pharmacists & Pharmacist Technicians

Learning level: 1

Accreditation Information

The American Pharmacists Association is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.  This activity is approved for 2.0 contact hours of CPE credit (0.20 CEUs). The ACPE Universal Activity Number for this activity is 0202-0000-19-144-H04-P/T.

To obtain credit for The 2018 ACC/AHA Guidelines for Cholesterol Management in Adult Patients, complete the assessment with a grade of 70% or better, complete the evaluation, and then claim credit. Participants need to have a valid username and password to claim credit. After credit has been claimed, please visit CPE monitor for your transcript.

APhA's continuing pharmacy education policy allows two opportunities to successfully complete the continuing pharmacy education assessment. Please note that the questions may not appear in the same order as printed and only two attempts to pass the assessment will be granted.  The current policy of the APhA Education Department is to not release the correct answers to any of our CPE tests. This policy is intended to maintain the integrity of the CPE activity and the assessment.

Initial release date: April 1, 2019
Expiration date: April 1, 2022 - NO CREDIT GRANTED AFTER THIS DATE


The 2018 ACC/AHA Guidelines for Cholesterol Management in Adult Patients is a home-study continuing education activity for pharmacists & pharmacist technicians developed by the American Pharmacists Association.

Advisory Board

Janelle F. Ruisinger, PharmD, FAPhA, Clinical Professor, Department of Pharmacy Practice
University of Kansas School of Pharmacy, Lawrence


Karen J. McConnell, PharmD, FCCP, BCPS-AQ Cardiology, ASH-CHC and APhA’s Government Affairs and editorial staff declare no conflicts of interest or financial interests in any product or service mentioned in this activity, including grants, employment, gifts, stock holdings, and honoraria. For complete staff disclosures, please see the Education and Accreditation Information section at


There is no fee associated with this activity for members of the American Pharmacists Association. There is a $25 fee for nonmembers.

System Requirements

Computer and internet access are required to complete this activity.  Please visit our website and view the Technology System Requirements to have a positive learning experience.